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Active Ingredients:Simvastatin

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking SIMVAR.

SIMVAR helps most people with high Cholesterol, but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor if you notice any of the following and they worry you:

  • constipation, diarrhoea, wind
  • stomach upset or pain, feeling sick (Nausea)
  • headache
  • dizziness

These are the more common side effects of SIMVAR. For the most part these have been mild and shortlived.

Tell your doctor immediately if you notice any of the following:

  • aching muscles, muscle tenderness or weakness, not caused by exercise
  • brown/black coloured urine

On rare occasions, muscle problems can be serious, including muscle breakdown resulting in kidney damage.

The risk of muscle problems is greater for:

  • patients taking higher doses of SIMVAR.
  • Older patients (65 years of age and older)
  • female patients
  • patients with abnormal kidney function and
  • patients with thyroid problems.

Tell your doctor immediately if you notice any of the following:

  • tingling in the hands or feet
  • yellowing of the skin and/or eyes, also called jaundice
  • signs of Anaemia, such as tiredness, being short of breath, and looking pale
  • Fever, generally feeling unwell
  • skin rash, itchiness
  • pinkish, itchy swellings on the skin, also called hives or nettlerash
  • painful, swollen joints
  • bruising more easily than normal
  • larger breasts than normal in men

These may be serious side effects of SIMVAR. Some of these may be symptoms of an allergic reaction to SIMVAR. You may need urgent medical attention. Serious side effects are rare.

Tell your doctor immediately or go to accident and emergency at your nearest hospital if you notice any of the following:

  • swelling of the face, lips, mouth, throat or tongue which may cause difficulty in swallowing or breathing
  • shortness of breath

These are serious side effects. If you have them, you may have had a serious allergic reaction to SIMVAR. You may need urgent medical attention or hospitalisation. Serious side effects are rare.

Also, tell your doctor if you notice:

  • hair loss
  • muscle cramps
  • trouble sleeping
  • poor memory
  • depression
  • erectile dysfunction
  • breathing problems including persistent cough and/or shortness of breath or fever

These are other side effects that have been reported with SIMVAR.

Liver problems can also occur and may be serious. Your doctor will do blood tests to check your liver.

Other side effects not listed above may also occur in some patients. Tell your doctor if you notice any other effects.

Do not be alarmed by this list of possible side effects. You may not experience any of them.

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