Active Ingredients:Dutasteride tamsulosin
DUODART is a combination of two medicines; dutasteride and tamsulosin hydrochloride. Dutasteride belongs to a group of medicines called 5-alpha reductase enzyme inhibitors and tamsulosin hydrochloride belongs to a group of medicines called alphablockers. These medicines can be used either alone or in combination in men who have a condition known as benign prostatic hyperplasia (BPH).
BPH is a non-cancerous enlargement of the prostate gland which is located at the lower portion of the urinary bladder surrounding the urethra (urine carrying tube). In men with BPH, the prostate gland becomes large enough to squeeze the urine tube running through it. If the urine tube is squeezed it narrows, making it more difficult for you to pass urine normally and you may have some or all of the following symptoms:
- difficulty in starting to urinate
- an interrupted, weak urinary stream
- more frequent urination, especially at night
- feeling that you need to urinate right away
- leaking or dribbling
- a feeling that you cannot empty your bladder completely.
As the disease progresses, untreated BPH can lead to an increased risk of complete blockage of urine flow (acute urinary retention) and/or the need for surgery.
Prostate growth is caused by a hormone in the blood called dihydrotestosterone (DHT). The dutasteride component of DUODART lowers DHT production in the body, leading to shrinkage of the enlarged prostate in most men. The tamsulosin hydrochloride component of DUODART acts by relaxing the smooth muscle in your prostate gland, making it easier to pass urine. Just as your prostate became large over a long period of time, reducing the size of your prostate and improving your symptoms may take time.
Your doctor may have prescribed DUODART for another reason. Ask your doctor if you are unsure why DUODART was prescribed for you.
DUODART is not addictive.